Salvestrol Cream is designed for topical use in combination with at least one capsule of encapsulated salvestrol per application. Salvestrol Cream does not work faster or better if more is applied; use only enough to lightly cover the affected area. Salvestrol Cream can be applied several times daily, depending on the severity of the problem, over as large an area as necessary, but should not be applied directly to an open sore. There are no known allergic reactions to Salvestrol Cream.